Drug Tree DataBase

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NOTE:

 The search page is designed to retrieve the results of similarity analysis, including cell line similarity, drug similarity, and cancer type similarity based on cell line similarity.

 (eg. Drug: Erlotinib)

Drug Id Drug Name Similarity Synonyms Target Target Pathway
1 Erlotinib 1.0 Tarceva, RG-1415, CP-358774, OSI-774, Ro-508231, R-1415 EGFR EGFR signaling
409 eEF2K Inhibitor, A-484954 0.210313658516266 NA eEF2K Other, kinases
408 Sphingosine Kinase 1 Inhibitor II 0.201505189595997 PF-543 Sphingosine Kinase Other, kinases
1262 UNC1215 0.192712366203598 UNC-1215 L3MBTL3 Chromatin other
119 Lapatinib 0.192328956461645 Tykerb, Tyverb EGFR, ERBB2 RTK signaling
91 GSK319347A 0.19011239550418 KIN001-135, IKK-3 inhibitor IKK Other, kinases
266 Zibotentan 0.190095527399177 ZD4054, ZD-4054 Endothelin-1 receptor (EDNRA) Other
447 ETP-45835 0.188171602001477 NA MNK1, MNK2 Other, kinases
197 Bryostatin 1 0.176899411449973 Bryostatin PKC Other
1114 Cetuximab 0.173491465662313 Erbitux, IMC-C225, C225, IMC-225, L01XC06 EGFR EGFR signaling
38 Saracatinib 0.171440940904827 AZD0530, AZD-0530, AZ-10353926 ABL, SRC Other, kinases
186 Bexarotene 0.155691964285714 LG-100069, Targretin, Targret, Targrexin, Targretyn, Bexarotenum Retinioic X receptor (RXR) agonist Other
202 GSK1904529A 0.154624851131401 GSK-1904529A, GSK 1904529A IGF1R, IR RTK signaling
1067 CCT007093 0.151395348837209 NA PPM1D Cell cycle
59 WZ-1-84 0.150601546834718 KIN001-123 BMX Other, kinases
1032 Afatinib 0.14871447902571 BIBW2992, Tovok, Gilotrif ERBB2, EGFR EGFR signaling
1175 Rucaparib 0.148027807163367 PF-01367338, AG-014699, AG-14447, AG-14699 PARP1, PARP2 Genome integrity
1377 Afatinib 0.147673347970819 BIBW2992, Tovok, Gilotrif ERBB2, EGFR EGFR signaling
154 CHIR-99021 0.147544230261421 CT 99021, CHIR99021, CHIR 99021 GSK3A, GSK3B WNT signaling
1264 SGC0946 0.146937427769523 NA DOT1L Chromatin histone methylation
Cell line Cosmic Id Similarity TCGA abbreviation
Cancer type Cluster Cellline number in this cluster (click to show celllines) P value
Cell line Cosmic Id Cluster TCGA abbreviation
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DTDB is developed by the Haiyun Wang's Lab at the School of Life Sciences and Technology, Tongji University, Shanghai, China.

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